課程資訊
課程名稱
早期胚胎發生學
Early Developmental Embryology 
開課學期
109-1 
授課對象
生命科學院  生命科學所  
授課教師
李士傑 
課號
LS5019 
課程識別碼
B21EU1320 
班次
 
學分
2.0 
全/半年
半年 
必/選修
選修 
上課時間
星期一3,4(10:20~12:10) 
上課地點
生科632 
備註
本課程以英語授課。
限學士班三年級以上
總人數上限:15人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1091LS5019_ 
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課程概述

Embryology is an old but fascinating subject. From the morphological
observation of chick embryo development to the unravel of the molecular
control of embryonic development in a variety of organisms, we have gone a
long way. However, the more we learn the less we know. It is a miracle to see
how a single cell develop into a fully functional adult. This course is design
to build the ground for students with interest in embryology. We will discuss
the basic principles and molecular controls of embryonic development. In
particular, we will emphasize the progression from immature gametes,
fertilization, cleavage to gastrulation (i.e. the formation of gut). The cell
fate and embryonic axis formation will also be included. The popular
experimental models used by current developmental biologist will also be
examined in detail. 

課程目標
1. Learn the developmental processes, regulatory mechanisms during embryogenesis.
2. Expose to developmental biology research by paper discussion
3. Stimulate scientific thinking by fomulating a proposal 
課程要求
1. Be on time
2. Active participation  
預期每週課後學習時數
 
Office Hours
另約時間 
指定閱讀
1. Developmental Biology, 2014. Tenth Edition. Scott F. Gilbert
2. Selected papers
 
參考書目
 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
Class performance 
10% 
Class attendence, asking and answering question, participation 
2. 
Midterm 
30% 
A comprehensive test regarding course materials.  
3. 
Paper Presentation 
30% 
A journal club oral presentation. 
4. 
Proposal 
30% 
A grant proposal in Developmental Biology 
 
課程進度
週次
日期
單元主題
Week 1
  Course Introduction  
Week 2
  Differential gene expression directs development  
Week 3
  Cell-cell communication in development  
Week 4
  Fertilization and egg activation  
Week 5
  Cleavage and Gastrulation 
Week 7
  Axis Specification 
Week 8
  Animal model systems used for developmental biology research 
Week 9
  Axis specification and pattern formation  
Week 10
  Midterm 
Week 11
  Research structure and proposal writing  
Week 12
  Ectoderm 
Week 13
  Neural crest cells and axonal specification  
Week 14
  Mesoderm 
Week 15
  Endoderm 
Week 16
  Proposal presentation I
Anna, Mark, Anniek,  
Week 17
  Proposal presentation II
Kayleigh,Huang, Yang, Luise  
Week 18
  Proposal presentation III 
Week 19
  Proposal due